What Are the Signs You Need Hormone Replacement Therapy?

March 12, 2025

Relentless hot flashes, mood swing struggles, and frequent low energy don’t have to be your new normal. Rejuvenessence’s Dr. Fred shares how these symptoms — and more — may indicate what are the signs that you need hormone replacement therapy (HRT).

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Blog. What Are the Signs You Need Hormone Replacement Therapy?

What Is Hormone Replacement Therapy (HRT)?

Hormone replacement therapy (HRT) is a medical treatment designed to replenish naturally declining hormone levels in women, particularly estrogen and progesterone, which can fluctuate dramatically during perimenopause, menopause, postpartum, or even due to stress. HRT is also administered for women diagnosed with certain thyroid conditions as well as women who have survived some forms of cancer.

Nearly all women will experience these physical and mental symptoms in life associated with hormone changes, but the severity differs. Consult with your doctor when it comes to understanding what are the signs that you need hormone replacement therapy, particularly when you experience symptoms such as fatigue, brain fog, hot flashes, and sleep disturbances on a near-daily basis.

Common Hormonal Imbalance Symptoms: When to Consider HRT

If you’re wondering what are the signs that you need hormone replacement therapy, consider the following symptoms, plus their toll on your daily well-being.

Persistent Fatigue and Low Energy

Ongoing exhaustion and sluggishness, even after a full night’s rest, may signal low estrogen and progesterone levels, each playing a key role in regulating metabolism and energy levels.

Mood Swings, Anxiety, or Depression

Hormonal shifts can impact neurotransmitters, leading to heightened irritability, anxiety, or even depressive episodes. What’s more, estrogen influences the brain’s serotonin production, which affects overall mood stability and risk of developing depression.

Sleep Disturbances

Trouble falling asleep, waking up frequently throughout the night, or restless sleep cycles can be linked to hormone imbalance in women, particularly progesterone, with its calming interactive effect on the body. Too little progesterone can negatively influence deep, restorative sleep.

Weight Gain and Difficulty Losing Weight

Unexplained weight gain, especially around the midsection, can result from hormonal changes that slow metabolism and influence fat storage as you age.

Hot Flashes and Night Sweats

As one of the most common hormonal side effects of menopause — sudden waves of heat and excessive sweating, especially at night — are hallmark signs of estrogen fluctuations affecting the body’s ability to regulate temperature.

Low Libido and Sexual Health Changes

A decline in estrogen can cause vaginal dryness, pain or discomfort during intimacy, or simply a noticeable drop in libido, making sexual health a big area of concern for many women experiencing hormonal imbalances.

Cognitive Issues, Causes of Brain Fog

Brain fog is often characterized by forgetfulness, difficulty concentrating, and general feelings of fatigue. Research suggests that estrogen underpins cognitive function by supporting neurotransmitters and influencing brain cell communication, meaning a drop in estrogen can impair your brain’s overall acuity.

Consulting a Doctor With Signs You Need Hormone Replacement Therapy

If symptoms are disrupting your daily life, know you’re not alone — many women experience notable mental and physical hormonal imbalance-based changes, especially during menopause. A knowledgeable doctor utilizing HRT therapy can help you find relief.

Tracking Symptoms and Recognizing Patterns

Start by documenting any and all symptoms. Note how often you experience things like hot flashes, sudden mood swings, sleep disturbances, and other concerns. Many women keep a symptom journal or digital log, which helps relay specific experiences and frequency to their doctor when assessing hormone fluctuations and possible treatment areas.

Undergo Hormone Medical Testing

Next, consider having your doctor perform blood tests to benchmark hormone levels, especially estrogen, progesterone, and testosterone. Your doctor may also evaluate thyroid function and adrenal gland health, which together help provide a more comprehensive look at your entire hormone profile and rule out chronic conditions or cancers.

Balancing Risks and Benefits of HRT

Ultimately, the decision to begin hormone replacement therapy is tailored to your lifestyle, your health goals, and your medical history. A trusted medical professional will help you weigh your specific benefits against any potential HRT risks, which are credibly low, creating an HRT regimen with dosages safest for you.

Get Relief With What Are the Signs That You Need Hormone Replacement Therapy?

HRT can provide significant results and ongoing lifestyle relief in ways few other treatments do — particularly how to manage hot flashes or when debating signs you need estrogen.

Long-Term Symptom Relief

HRT treatments are entirely designed to restore individual hormonal balance, alleviating women’s health issues like hot flashes, brain fog, night sweats, low libido, and emotional mood swings — all for you to feel more like yourself again.

Improved Quality of Sleep and Energy Levels

With newly stabilized hormones, many women report better sleep quality and more energy throughout the day, reducing previous symptoms of chronic fatigue and sluggishness.

Enhanced Sexual Health

HRT helps combat low libido, vaginal dryness, and related pain or discomfort during sexual activity, reintroducing a fulfilling and pleasurable intimate life back to women.

Supporting Cognitive Function

Research has linked estrogen to memory support, focus, and mental clarity. By restoring estrogen hormone profiles, HRT may improve cognitive performance protecting against common age-related brain health decline.

Learn the Signs You Need Estrogen, NJ Hormone Therapy

If any of these symptoms are familiar, it may be time to begin exploring hormone replacement therapy options.

Rejuvenessence’s Dr. Fred Coville has over two decades of experience helping women and men regain their lives through personalized hormone replacement therapy. His knowledgeable support and detailed approach to wellness ensure a treatment best aligned with what you’re looking for.

Don’t let menopause, perimenopause, or lifestyle changes hold you back. Schedule a consultation with Dr. Fred today to learn how HRT can help you feel energized, vibrant, and ultimately back in control.

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